grip question..

Time to get off the computer and head to the range. The weather here is lousy and I will be going indoors today. I've been inspired by @Sterling Archer's ammo tests and will today be conducting my own, much less sophisticated, version. Me and my DW will be shooting some Speer Gold Dot JHPs for...

Maybe a foolish one but... anybody ever try a full size grip on the right side, kind of like a palm swell, but with a slim on the left (right hand shooter)? I dont have large hands, but prefer no empty space in my dominate hand grip Just ask'in ... Thanks for your thoughts.