There is a medical distinction between Guts and Balls. We've heard colleagues referring to people with Guts, or with Balls. However, do they know the difference between them? Here's the official distinction; straight from the British Medical Journal: Volume 323; page 295. GUTS - Is arriving home late, after a night out with the guys, being met by your wife with a broom, and having the Guts to ask: Are you still cleaning, or are you flying somewhere? BALLS - Is coming home late after a night out with the guys, smelling of perfume and beer, lipstick on your collar, slapping your wife on the butt and having the Balls to say: "You're next, Chubby" I trust this clears up any confusion. Medically speaking, there is no difference in the outcome; both are fatal.